Injectable (Syringe Pro)

    Syringe testing is a necessary step in manufacturing prefilled syringes commercially. Automating this process eliminates human error, providing consistent results. Astech have developed an automated solution to carry out unattended high throughput batch testing of prefilled syringes. The Syringe Pro® system incorporates automation modules for preparation, testing and analysis depending on the product being tested, and the methods to be incorporated.

    Benefits of pre-filled syringes

    A growing number of drugs and vaccines are available in prefilled syringes. The manufacture and supply of prefilled syringe products is highly regulated to minimise chemical and physical changes and maintain drug efficacy. Compared to oral administration, parenteral drug delivery provides rapid drug absorbed and avoids first-pass metabolism, or enzymatic degradation. This leads to better bioavailability, and more predictable pharmaco-dynamic and pharmacokinetic profiles. Compared to traditional parenteral delivery, prefilled syringes are easy to use, eliminate dosing errors and are not wastefully overfilled.

    Automate syringe testing with SyringePro

    Testing is an important step in the manufacturing process for prefilled syringes to ensure product quality and stability. Patient safety, drug stability, and ease of filling are being addressed with new designs and coatings and materials. Astech’s Syringe Pro system is designed to provide safe, high throughput, testing of prefilled syringe products for the highly regulated parenteral drug market.


    Examples of the type of equipment included within the system are as follows:

    • Device Loading Tray Area

    • Syringe Carousel

    • Syringe Sheath Removal Station

    • Syringe Deposit Station

    • Solvent Dispense Station

    • Automated needle/tip wash

    • Vortexer

    • HPLC interface

    • Liquid Handling System (includes HPLC injection valve)


    The system is fully enclosed with the option of including environmental control or extraction. Syringe Pro® systems can be controlled by a modular software solution based around Astech’s proven architecture. This software solution is designed to run syringe test methods specific to your requirements, and can include compliance to 21 CFR Part 11 if required. Operators simply load the system with a batch of prefilled syringes from the production line and select the required test protocol for each syringe via the GUI. The system automatically performs testing and report analysis results back to the database. The main components of the software system are as follows:

    • Control Server

    • Database Schema

    • Graphical User Interface (GUI)

    Discover more about Astech

    Explore our Respiratory Applications, Products plus REACTS

    Respiratory Applications

    See what is possible with our wide range of respiratory applications including our 'X' products.


    Explore our products which are customisable and scalable to meet your laboratory or facilities specifications.

    REACTS Support & Maintenance

    Find our more about our REACTS service which offers Rapid, Effective And Complete Technical Support for all your automation equipment.

    Get in contact with us

    INFO@ASTECHPROJECTS.CO.UK +44 1928 571 797
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